Department of Zoology
Dr. Poornima Kkani
Ph.D (Assistant Professor
poornimakkani_zool@tcarts.in
2013-12-23
Educational Background
- M.sc. Applied psychology (2016-2018)
(Annamalai University, Chidambaram, Tamil Nadu) - Ph.D. Zoology (Degree awarded on 20 th Oct, 2012)
Madurai Kamaraj University, Lady Doak College, Madurai
Title: “A Study on the Efficacy of Specific Proteins from Indigenous Bacillus
thuringiensis Strains on Human Cancer Cell Lines”. - M.Sc. Zoology Madurai Kamaraj University, Lady Doak College
Project title: “Efficacy of antimicrobial activity of different parts of Calotropis
gigantia” - B.Sc. Zoology
(Kerala University, N.S.S.College, Trivandrum) - Pre-Degree (HSLC)
Kerala University, All Saint’s college, Trivandrum. - S.S.L.C
Kerala State Educational Board, Carmel Girl’s High School,Trivandrum.
Professional Experience
- 2011-2013 : Assistant Professor in the Department of Biotechnology, Lady Doak College, Madurai.
- 2013-till date : Assistant Professor in the Department of Zoology and Microbiology, Thiagarajar
College, Madurai.
Awards & Recognitions
- Cleared National Eligibility test CSIR-NET in 2004 June.
- Awarded Tamil Nadu State Collegiate Science and Technology fellowship for two
years from 2006-2008. - Indian National Science Academy Summer Research Fellow in 2016 to Rajiv Gandhi
Institute of Biotechnology, Thiruvananthapuram
Research Publications
Publications
- Steffy, A., Shakina, J., Sujatha, R.Saravanan, Karthikeyan M., M.Saravanan,
Poornima Kkani and Tharmaraj P. et al. A Novel Bisimine (4,6-Triazolyl, 2-
Phenylamino,1,3,5-Triazine) Serving as Potential Anticancer Agent and
Chemosensor for the Sensitive Colorimetric Detection of Cu(II) Ion: Design,
Synthesis, and Biological Evaluation of Therapeutic Efficiency. Chemistry Africa 8,
4957–4972 (2025). - Singh M, Pradhan D, Kkani P, Prasad Rao G, Dhagudu NK, Kumar L,
Ramasubramanian C, Kumar SG, Sonttineni S and Mohan KN (2023) Genome-scale
copy number variant analysis in schizophrenia patients and controls from South
India. Front. Mol. Neurosci. 16:1268827. doi: 10.3389/fnmol.2023. - Saxena S, Maroju PA, Choudhury S, Voina VC, Naik P, Gowdhaman K, Kkani P,
Chennoju K, Ganesh Kumar S, Ramasubramanian C, Prasad Rao G, Jamma T,
Narayan KP, Mohan KN. Functional Analysis of DNMT1 SNPs
(rs2228611 and rs2114724) Associated with Schizophrenia. Genet Res (Camb). 2021
Mar 31;2021 - Sonal Saxena, Poornima Kkani , Chellamuthu Rama Subramanian C, Ganesh Kumar
S. and Kommu Naga Mohan (2019) Analysis of 15.q 11.2 CNVs in an Indian
population with schizophrenia, Ann Hum Gen: 1-5. - Periyasamy, A., Kkani, Poornima., Chandrasekaran, B., Suguna P.,Saranya V., Peter
S., and Shenbagarathai R., (2016) Screening and characterization of a non-insecticidal
Bacillus thuringiensis strain producing parasporal protein with selective toxicity
against human colon cancer cell lines, Ann Microbiol 66: 1167-1178. IF: 1.23 - Abirami P., Poornima Kkani., Suguna P., Saranya V., Selvanayagam P., and
Shenbagarathai R., (2016) Phenotypic characterisation of indigenous Bacillus
thuringiensis strain (B.t. LDC 501) expressing cancer cell killing protein, journal of
Exptal Biol and Agri Sci. 4: 232-241. - Saranya V. Rajeswari, P. Abirami, Poornima kkani, P. Suguna and R.Shenbagarathai
(2015) Statistical media design for efficient poly hydroxyalkanoate production in
pseudomonas sp. MNNG-S, Prep Biochem And Biotechnol, 46: 446-453. - Sonal Saxena, Kavitha Gowdhaman, Poornima Kkani, Bhavyasri Vennapusa,
Chellamuthu Rama Subramanian C, Ganesh Kumar S. and Kommu Naga Mohan
(2015) Improved multiplex Ligation-dependent Probe Amplification (i-MLPA) for
rapid copy number variant detection, Clin. Chim. Acta: 450, 19-24. - Saranya.V., Poornima kkani., Krishnakumari.M.S., Suguna.P., Binuramesh.C.,
Abirami.P., Rajeswari.V., Ramachandran.K.B. and Shenbagarathai.R (2012)
Quantification of intracellular Polyhydroxyalkanoates by virtue of personalized flow
cytometry protocol. Current Microbiology. 589-594. - Ayyasamy Mahalakshmi, Kabilan Sujatha, Poornima Kkani, Rajaiah Shenbagarathai,
Distribution of cry and cyt Genes among Indigenous Bacillus thuringiensis Isolates with
Mosquitocidal Activity (2012) Advances in Microbiolog. 2, 216-226. - Kkani Poornima, Viswanathan Saranya, Periyasamy Abirami, Chandrasekaran
Binuramesh Ponnusamy Suguna, Peter Selvanayagam, Rajaiah Shenbagarathai (2012)
Phenotypic and genotypic characterization of B.t.LDC-391 strain that produce cytocidal
proteins against human cancer cells. Bioinformation. 8(10): 461-465. Poornima Kkani, Peter Selvanayagam and Shenbagarathai.R, (2010). Identification of
native Bacillus thuringiensis strain from South India having specific cytocidal activity
against cancer cells. Journal of Applied Microbiology (109) 2010.CONFERENCES:
- PAPERS PRESENTED IN NATIONAL AND INTERNATIONAL CONFERENCES:
Abirami P., Poornima Kkani, C. Binuramesh, Suguna P. and Shenbagarathai R,
Screening of novel B.t. strains from southern coastal regions of Inida & quot;, I st International
conference on Bioengineering, SASTRA UNIVERSITY, Tanjore, Tamil Nadu on 8-9
Aug, 2013.
Poornima Kkani, Peter Selvanayagam and Shenbagarathai Rajiah, “Proteomic analysis
of cancer specific cytotoxic proteins from B.thuringiensis LDC-391”, 110 th general
meeting of American Society for Microbiology in San-Diego, California, U.S.A. May 23 rd
–May 27 th 2010.
Poornima Kkani, Peter Selvanayagam and Shenbagarathai Rajiah, “Identification of a
parasporin producing Bacillus thuringiensis isolate from Madurai, Tamil Nadu”, Science
Day and Aqua-terr annual conference on organismal & functional genomics, Madurai
Kamaraj University, Madurai 6 th March 2010.
A.Mahalakshmi, K. Sujatha, Poornima Kkani, M. Tamilarasi, G. Geetha, K. Anburani
and R. Shenbagarathai (2007 “Economical B.t. toxin production from cane molasses by
B.t LDC-9 M70.” in the “International conference on new horizons in biotechnology
(NHBT-2007), NIST, Trivandrum, India Nov 26-29, 2007.” - Poornima Kkani, A.Mahalakshmi, K. Sujatha and R. Shenbagarathai (2006)
“Comparative analysis of insecticidal and non-insecticidal strains of Bacillus
thuringiensis using molecular methods” in the ‘4 th International symposium on
Biocontrol and Biotechnology” from 27 th to 29 th November, Lady Doak college,
Madurai.” - A. Mahalakshmi, Poornima Kkani, K. Sujatha and R. Shenbagarathai (2006). “A
comparative Bioinformatics analysis of wild type and MNNG mutant cry 10AA protein
in Bacillus thuringiensis LDC-9” in the “International symposium on vector control and
vector borne diseases” from 13 th to 15 th October, Madurai, India. - R. Shenbagarathai, A.Mahalakshmi, K.Sujatha and Poornima Kkani. (2005) “ITS and
REP based identification of novel indigenous B.thuringiensis strains from Madurai
district “Third International Symposium On Biocontrol And Biotechnology”, Wuhan,
China, from May 10 to 13. - A.Mahalakshmi, Poornima Kkani, R. Shenbagarathai and K.Sujatha. (2005) Presented a
paper on “Insecticidal efficacy of indigenous isolates of Bacillus thuringiensis in the
management of the vectors, Culex quinquefasciatus and Aedes aegypti” at the “Third
International Symposium On Biocontrol And Biotechnology”, Wuhan, China, from
May 10 to 13. - Poornima Kkani, A.Mahalakshmi, R. Shenbagarathai and K.Sujatha (2005) Presneted a
paper on “Media optimization for a highly insecticidal indigenous isolate of
B.thuringiensis for delta endotoxin crystal production” in the “Third International
Symposium On Biocontrol And Biotechnology”, Wuhan, China, from May 10 to13. - R. Shenbagarathai, K. Sujatha, A.Mahalakshmi and Poornima Kkani. (2005), Paper
presented on “Production and Characterization of PolyHydroxyAlkanoates (PHA) by
Pseudomonas sp LDC-5 and LDC-25 from waste products” in the “International Conference on Advances in Polymer Blends, Composites, IPNS and GELS: Macro to
Nano Scales”, Kottayam, Kerala, from 21 st to 23 rd March, (2005) K.Sujatha, R. Shenbagarathai, A.Mahalakshmi and Poornima Kkani. (2005),“Purification and Properties of PolyHydroxyAlkanoates (PHA) from Pseudomonas sp LDC-5 & LDC-25” in the “International Conference on Advances in Polymer Blends,
Composites, IPNS and GELS: Macro to Nano Scales”, Kottayam, Kerala, from 21 st to 23 rd
March.Workshops Organised:
1. Two days National workshop in :Multiplex Ligation based Probe
amplification technique at Thiagarajar College in Dec 20 th and 21 st 2015.
2. Resource person for National Workshop in Animal Cell culture techniques at
Lady Doak College, 2016 and 2018.
3. Resource Person for National workshop on “Molecular Biology techniques
and computational Biology” at Thiagarajar College in August 2019.
Professional Memberships
Membership in Scientific organizations:
- Life member in Indian Society for Human Genetics (ISHG)
- Life member in Indian association for Cancer Research (IACR)
Life member in Biotech Research Society of India (BRSI)